Gluten Ataxia

Gluten ataxia is an autoimmune neurological condition characterized by damage to the cerebellum, the part of the brain responsible for coordination and motor control. It presents with progressive difficulty with balance, coordination, and fine motor skills. Gluten ataxia occurs when antibodies produced against gluten cross-react with cerebellar tissues, particularly through antibodies targeting transglutaminase-6, which is primarily expressed in the brain. This condition can occur with or without intestinal symptoms or damage, meaning clients may have negative conventional celiac testing despite significant neurological impairment. Early recognition and strict gluten elimination are essential, as neurological damage may become irreversible if treatment is delayed. Studies have demonstrated that cerebellar atrophy can be halted, and in some cases, neurological function can improve with strict dietary compliance.

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